§558.128. Chlortetracycline.
21 C.F.R. § 558.128
Specifications. Type A medicated articles containing either chlortetracycline calcium complex equivalent to chlortetracycline hydrochloride, or for products intended for use in milk replacer, chlortetracycline hydrochloride.
Sponsors. See sponsors in § 510.600(c) of this chapter as follows:
No. 054771— 50, 70, 80, 90, or 100 grams per pound (g/lb) Type A medicated article.
No. 066104— 10, 20, 30, 50, 70, or 100 g/lb of Type A medicated article.
No. 069254— 50, 90, or 100 g/lb of Type A medicated article.
Related tolerances. See § 556.150 of this chapter.
Special considerations.
Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. See § 558.6 for additional requirements.
The expiration date of VFDs for chlortetracycline medicated feeds must not exceed 6 months from the date of issuance. VFDs for chlortetracycline shall not be refilled.
In milk replacers or starter feed; include on labeling the warning— “A withdrawal period has not been established for this product in preruminating calves. Do not use in calves to be processed for veal.”
Manufacture for use in free-choice feeds as in paragraph (e)(4)(vi) of this section must conform to § 510.455 of this chapter.
When manufactured for use as in paragraph (e)(5)(iii) of this section, include on labeling the warning: “Psittacosis, avian chlamydiosis, or ornithosis is a reportable communicable disease, transmissible between wild and domestic birds, other animals, and man. Contact appropriate public health and regulatory officials.”
Conditions of use—
Chickens. It is used as follows:
Turkeys. It is used as follows:
Swine. It is used as follows:
Cattle. It is used as follows:
Minor species. It is used as follows:
It is used as a free-choice, loose mineral Type C feed as follows—
Specifications.
Amount. 6,000 grams per ton.
Indications for use. Beef and nonlactating dairy cattle: As an aid in the control of active infection of anaplasmosis caused by Anaplasma marginale susceptible to chlortetracycline.
Limitations. Feed continuously on a free-choice basis at a rate of 0.5 to 2.0 mg chlortetracycline per pound of body weight per day.
Sponsors. See Nos. 054771 and 069254 in § 510.600(c) of this chapter.
Notes, amendments, and revision history
Amendments
[81 FR 94995, Dec. 27, 2016, as amended at 82 FR 21691, May 10, 2017; 82 FR 43485, Sept. 18, 2017; 83 FR 13636, Mar. 30, 2018; 83 FR 14588, Apr. 5, 2018; 83 FR 48947, Sept. 28, 2018; 83 FR 64741, Dec. 18, 2018; 84 FR 8975, Mar. 13, 2019; 84 FR 39185, Aug. 9, 2019; 86 FR 13189, Mar. 8, 2021; 86 FR 14822, Mar. 19, 2021; 86 FR 17064, Apr. 1, 2021; 86 FR 57999, Oct. 20, 2021; 86 FR 61686, Nov. 8, 2021; 87 FR 58963, Sept. 29, 2022; 87 FR 76422, Dec. 14, 2022; 88 FR 14901, Mar. 10, 2023; 88 FR 55567, Aug. 16, 2023; 89 FR 14411, Feb. 27, 2024; 89 FR 95103, Dec. 2, 2024; 90 FR 6801, Jan. 21, 2025]
Authority
Authority: 21 U.S.C. 354, 360b, 360ccc, 360ccc-1, 371.
Source
Source: 40 FR 13959, Mar. 27, 1975, unless otherwise noted.
Amendments
[81 FR 94995, Dec. 27, 2016, as amended at 82 FR 21691, May 10, 2017; 82 FR 43485, Sept. 18, 2017; 83 FR 13636, Mar. 30, 2018; 83 FR 14588, Apr. 5, 2018; 83 FR 48947, Sept. 28, 2018; 83 FR 64741, Dec. 18, 2018; 84 FR 8975, Mar. 13, 2019; 84 FR 39185, Aug. 9, 2019; 86 FR 13189, Mar. 8, 2021; 86 FR 14822, Mar. 19, 2021; 86 FR 17064, Apr. 1, 2021; 86 FR 57999, Oct. 20, 2021; 86 FR 61686, Nov. 8, 2021; 87 FR 58963, Sept. 29, 2022; 87 FR 76422, Dec. 14, 2022; 88 FR 14901, Mar. 10, 2023; 88 FR 55567, Aug. 16, 2023; 89 FR 14411, Feb. 27, 2024; 89 FR 95103, Dec. 2, 2024; 90 FR 6801, Jan. 21, 2025]