---
kind: "section"
citation: "42 U.S.C. § 285l–5"
title: "42"
title_heading: "The Public Health and Welfare"
number: "285l–5"
heading: "Application"
release: "119-102"
date: "2026-07-12"
url: "https://uscodex.org/usc/42/285l-5"
units:
  - "Chapter 6A — Public Health Service"
  - "Subchapter III — National Research Institutes"
  - "Part C — Specific Provisions Respecting National Research Institutes"
  - "Subpart 12 — national institute of environmental health sciences"
---

# §285l–5. Application

- (a) **Application—** Sections [285l–2](/usc/42/285l–2.md) to 285l–5 of this title shall not apply to research, including research performed using biotechnology techniques, or research related to the causes, diagnosis, [treatment](/usc/42/11851.md?p=11), control, or prevention of physical or mental diseases or impairments of humans or animals.
- (b) **Use of test methods—** Nothing in sections [285l–2](/usc/42/285l–2.md) to 285l–5 of this title shall prevent a Federal [agency](/usc/42/8262.md?p=1) from retaining final authority for incorporating the test methods recommended by the ICCVAM in the manner determined to be appropriate by such Federal [agency](/usc/42/8262.md?p=1) or regulatory body.
- (c) **Limitation—** Nothing in sections [285l–2](/usc/42/285l–2.md) to 285l–5 of this title shall be construed to require a [manufacturer](/usc/42/300aa–33.md?p=3) that is currently not required to perform animal testing to perform such tests. Nothing in sections [285l–2](/usc/42/285l–2.md) to 285l–5 of this title shall be construed to require a [manufacturer](/usc/42/300aa–33.md?p=3) to perform redundant endpoint specific testing.
- (d) **Submission of tests and data—** Nothing in sections [285l–2](/usc/42/285l–2.md) to 285l–5 of this title precludes a party from submitting a test method or scientific data directly to a Federal [agency](/usc/42/8262.md?p=1) for use in a regulatory [program](/usc/42/274l–1.md?p=4).

## Source credit

(Pub. L. 106–545, § 5, Dec. 19, 2000, 114 Stat. 2724.)

## Notes

### Editorial Notes

### Codification

Section was enacted as part of the ICCVAM Authorization Act of 2000, and not as part of the Public Health Service Act which comprises this chapter.