---
kind: "section"
citation: "42 U.S.C. § 285l–1"
title: "42"
title_heading: "The Public Health and Welfare"
number: "285l–1"
heading: "Applied Toxicological Research and Testing Program"
release: "119-102"
date: "2026-07-12"
url: "https://uscodex.org/usc/42/285l-1"
units:
  - "Chapter 6A — Public Health Service"
  - "Subchapter III — National Research Institutes"
  - "Part C — Specific Provisions Respecting National Research Institutes"
  - "Subpart 12 — national institute of environmental health sciences"
---

# §285l–1. Applied Toxicological Research and Testing Program

- (a) There is established within the Institute a [program](/usc/42/274l–1.md?p=4) for conducting applied research and testing regarding toxicology, which [program](/usc/42/274l–1.md?p=4) shall be known as the Applied Toxicological Research and Testing [Program](/usc/42/274l–1.md?p=4).
- (b) In carrying out the [program](/usc/42/274l–1.md?p=4) established under [subsection (a)](#a), the [Director](/usc/42/11851.md?p=5) of the Institute shall, with respect to toxicology, carry out activities—
  - (1) to expand knowledge of the health effects of environmental agents;
  - (2) to broaden the spectrum of toxicology information that is obtained on selected chemicals;
  - (3) to develop and validate assays and protocols, including alternative methods that can reduce or eliminate the use of animals in acute or chronic safety testing;
  - (4) to establish criteria for the validation and regulatory acceptance of alternative testing and to recommend a process through which scientifically validated alternative methods can be accepted for regulatory use;
  - (5) to communicate the results of research to government [agencies](/usc/42/8262.md?p=1), to medical, scientific, and regulatory communities, and to the public; and
  - (6) to integrate related activities of the Department of Health and Human [Services](/usc/42/201.md?p=a).

## Source credit

(July 1, 1944, ch. 373, title IV, § 463A, as added Pub. L. 103–43, title XIII, § 1301(a), June 10, 1993, 107 Stat. 169.)