---
kind: "section"
citation: "9 C.F.R. § 113.42"
title: "9"
number: "113.42"
heading: "Detection of lymphocytic choriomeningitis contamination."
url: "https://uscodex.org/cfr/9/113.42"
---

# §113.42. Detection of lymphocytic choriomeningitis contamination.


The test for detection of lymphocytic choriomeningitis (LCM) virus provided in this section shall be conducted when such a test is prescribed in an applicable Standard Requirement or in a filed Outline of Production. Vaccine virus may be neutralized with specific antiserum when necessary.

- (a) Each of at least 10 mice obtained from a source free of LCM shall be injected in the footpad of a hindfoot with 0.02 ml of the material being tested and observed each day for 21 days.
- (b) If any of the mice show swelling in the injected footpad or if more than one becomes systemically abnormal, the material being tested is unsatisfactory.

## Notes

### Amendments

[42 FR 6794, Feb. 4, 1977]

### Authority

Authority: 21 U.S.C. 151-159; 7 CFR 2.22, 2.80, and 371.4.

### Source

Source: 34 FR 18004, Nov. 7, 1969, unless otherwise noted.

### Amendments

[42 FR 6794, Feb. 4, 1977]