---
kind: "unit"
title: "45"
title_heading: "Public Welfare"
key: "subtA/subchA/part100"
level: "part"
label: "Part 100"
heading: "Intergovernmental Review of Department of Health and Human Services Programs and Activities"
release: "ecfr-current"
date: "2026-08-27"
url: "https://uscodex.org/cfr/45/subtA-subchA-part100"
sections_count: 13
---

# Part 100 — Intergovernmental Review of Department of Health and Human Services Programs and Activities

Title 45 C.F.R. — Public Welfare › Subtitle A — Department of Health and Human Services › Subchapter A — General Administration

## Sections

- [§100.1. What is the purpose of these regulations?](/cfr/45/100.1.md)
- [§100.2. What definitions apply to these regulations?](/cfr/45/100.2.md)
- [§100.3. What programs and activities of the Department are subject to these regulations?](/cfr/45/100.3.md)
- [§100.4. Reserved](/cfr/45/100.4.md)
- [§100.5. What is the Secretary's obligation with respect to Federal interagency coordination?](/cfr/45/100.5.md)
- [§100.6. What procedures apply to the selection of programs and activities under these regulations?](/cfr/45/100.6.md)
- [§100.7. How does the Secretary communicate with state and local officials concerning the Department's programs and activities?](/cfr/45/100.7.md)
- [§100.8. How does the Secretary provide states an opportunity to comment on proposed Federal financial assistance and direct Federal development?](/cfr/45/100.8.md)
- [§100.9. How does the Secretary receive and respond to comments?](/cfr/45/100.9.md)
- [§100.10. How does the Secretary make efforts to accommodate intergovernmental concerns?](/cfr/45/100.10.md)
- [§100.11. What are the Secretary's obligations in interstate situations?](/cfr/45/100.11.md)
- [§100.12. How may a state simplify, consolidate, or substitute federally required state plans?](/cfr/45/100.12.md)
- [§100.13. May the Secretary waive any provision of these regulations?](/cfr/45/100.13.md)