---
kind: "section"
citation: "29 C.F.R. § 1990.112"
title: "29"
number: "1990.112"
heading: "Classification of potential carcinogens."
url: "https://uscodex.org/cfr/29/1990.112"
---

# §1990.112. Classification of potential carcinogens.


The following criteria for identification, classification and regulation of potential occupational carcinogens will be applied, unless the Secretary considers evidence under the provisions of §§ [1990.143](/cfr/29/1990.143.md), [1990.144](/cfr/29/1990.144.md) and [1990.145](/cfr/29/1990.145.md) and determines that such evidence warrants an exception to these criteria.

- (a) **Category I Potential Carcinogens.** A substance shall be identified, classified, and regulated as a Category I Potential Carcinogen if, upon scientific evaluation, the Secretary determines that the substance meets the definition of a potential occupational carcinogen in (1) humans, or (2) in a single mammalian species in a long-term bioassay where the results are in concordance with some other scientifically evaluated evidence of a potential carcinogenic hazard, or (3) in a single mammalian species in an adequately conducted long-term bioassay, in appropriate circumstances where the Secretary determines the requirement for concordance is not necessary. Evidence of concordance is any of the following: positive results from independent testing in the same or other species, positive results in short-term tests, or induction of tumors at injection or implantation sites.
- (b) **Category II Potential Carcinogens.** A substance shall be identified, classified, and regulated as a Category II Potential Carcinogen if, upon scientific evaluation, the Secretary determines that:
  - (1) The substance meets the criteria set forth in [§ 1990.112(a)](#a), but the evidence is found by the Secretary to be only “suggestive”; or
  - (2) The substance meets the criteria set forth in [§ 1990.112(a)](#a) in a single mammalian species without evidence of concordance.

## Notes

### Authority

Authority: Secs. 4, 6, 8, Occupational Safety and Health Act of 1970 (29 U.S.C. 653, 655, 657); Secretary of Labor's Order No. 8-76 (41 FR 25059); and 29 CFR part 1911.

### Source

Source: 45 FR 5282, Jan. 22, 1980, unless otherwise noted.