---
kind: "section"
citation: "22 C.F.R. § 313.4"
title: "22"
number: "313.4"
heading: "Definition of “significant guidance document.”"
url: "https://uscodex.org/cfr/22/313.4"
---

# §313.4. Definition of “significant guidance document.”

- (a) A “significant guidance document” is a guidance document that will be disseminated to the general public and that may reasonably be anticipated:
  - (1) To lead to an annual effect on the economy of $100 million or more or adversely affect in a material way the U.S. economy, a sector of the U.S. economy, productivity, competition, jobs, the environment, public health or safety, or State, local, or tribal governments or communities;
  - (2) To create serious inconsistency or otherwise interfere with an action taken or planned by another Federal agency;
  - (3) To alter materially the budgetary impact of entitlements, grants, user fees, or loan programs or the rights and obligations of recipients thereof; or
  - (4) To raise novel legal or policy issues arising out of legal mandates, the President's priorities, or the principles set forth in E.O. 12866, as further amended.
- (b) The term “significant guidance document” does not include the categories of documents excluded by [§ 313.1(c)](/cfr/22/313.1.md?p=c) or any other category of guidance documents exempted by the Agency in consultation with the Office of Management and Budget, Office of Information and Regulatory Affairs (OMB/OIRA).
- (c) Significant guidance documents must be reviewed by OMB/OIRA under E.O. 12866 before issuance; and must demonstrate compliance with the applicable requirements for regulations or rules, including significant regulatory actions, set forth in E.O. 12866, E.O. 13563, E.O. 13609, E.O. 13771 and E.O. 13777.

## Notes

### Authority

Authority: 22 U.S.C. 2501 et seq.

### Source

Source: 85 FR 73419, Nov. 18, 2020, unless otherwise noted.