---
kind: "section"
citation: "21 C.F.R. § 558.59"
title: "21"
number: "558.59"
heading: "Apramycin."
url: "https://uscodex.org/cfr/21/558.59"
---

# §558.59. Apramycin.

- (a) **Specifications.** Type A articles containing 75 grams apramycin (as apramycin sulfate) per pound.
- (b) **Sponsor.** See No. 058198 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
- (c) **Related tolerances.** See [§ 556.52](/cfr/21/556.52.md) of this chapter.
- (d) **Special considerations.**
  - (1) Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian. See [§ 558.6](/cfr/21/558.6.md) for additional requirements.
  - (2) The expiration date of VFDs for apramycin medicated feeds must not exceed 6 months from the date of issuance. VFDs for apramycin shall not be refilled.
- (e) **Conditions of use in swine—**

## Notes

### Amendments

[81 FR 94995, Dec. 27, 2016, as amended at 87 FR 10970, Feb. 28, 2022]

### Authority

Authority: 21 U.S.C. 354, 360b, 360ccc, 360ccc-1, 371.

### Source

Source: 40 FR 13959, Mar. 27, 1975, unless otherwise noted.

### Amendments

[81 FR 94995, Dec. 27, 2016, as amended at 87 FR 10970, Feb. 28, 2022]