---
kind: "section"
citation: "21 C.F.R. § 556.344"
title: "21"
number: "556.344"
heading: "Ivermectin."
url: "https://uscodex.org/cfr/21/556.344"
---

# §556.344. Ivermectin.

- (a) **Acceptable daily intake (ADI).** The ADI for total residue of ivermectin is 5 µg/kg of body weight per day.
- (b) **Tolerances.** The tolerances for 22,23-dihydroavermectin B1a (marker residue) are:
  - (1) **American bison.** Liver (target tissue): 15 ppb.
  - (2) **Cattle.**
    - (i) **Liver (target tissue)—** 1.6 ppm.
    - (ii) **Muscle—** 650 ppb.
  - (3) **Reindeer.** Liver (target tissue): 15 ppb.
  - (4) **Sheep.** Liver (target tissue): 30 ppb.
  - (5) **Swine.**
    - (i) **Liver (target tissue)—** 20 ppb.
    - (ii) **Muscle—** 20 ppb.
- (c) **Related conditions of use.** See §§ [520.1192](/cfr/21/520.1192.md), [520.1195](/cfr/21/520.1195.md), [520.1197](/cfr/21/520.1197.md), [522.1192](/cfr/21/522.1192.md), [522.1193](/cfr/21/522.1193.md), [524.1193](/cfr/21/524.1193.md), and [558.300](/cfr/21/558.300.md) of this chapter.

## Notes

### Amendments

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]

### Authority

Authority: 21 U.S.C. 342, 360b, 371.

### Source

Source: 84 FR 32993, July 11, 2019, unless otherwise noted.

### Amendments

[84 FR 32993, July 11, 2019, as amended at 85 FR 18121, Apr. 1, 2020]