---
kind: "section"
citation: "21 C.F.R. § 556.113"
title: "21"
number: "556.113"
heading: "Ceftiofur."
url: "https://uscodex.org/cfr/21/556.113"
---

# §556.113. Ceftiofur.

- (a) **Acceptable daily intake and acute reference dose—**
  - (1) **Acceptable daily intake (ADI).** The ADI for total residue of ceftiofur is 30 µg/kg of body weight per day.
  - (2) **Acute reference dose (ARfD).** The ARfD for total residue of ceftiofur is 0.830 mg/kg of body weight.
- (b) **Tolerances.** The tolerances for desfuroylceftiofur (marker residue) are:
  - (1) **Cattle.**
    - (i) **Kidney (target tissue)—** 0.4 ppm.
    - (ii) **Liver—** 2 ppm.
    - (iii) **Muscle—** 1 ppm.
    - (iv) **Milk—** 0.1 ppm.
  - (2) **Chickens and turkeys.** Edible tissues (excluding eggs): Not required.
  - (3) **Goats.**
    - (i) **Kidney (target tissue)—** 8 ppm.
    - (ii) **Liver—** 2 ppm.
    - (iii) **Muscle—** 1 ppm.
    - (iv) **Milk—** 0.1 ppm.
  - (4) **Sheep.** Edible tissues (excluding milk): Not required.
  - (5) **Swine.**
    - (i) **Kidney (target tissue)—** 0.25 ppm.
    - (ii) **Liver—** 3 ppm.
    - (iii) **Muscle—** 2 ppm.
- (c) **Related conditions of use.** See §§ [522.313a](/cfr/21/522.313a.md), [522.313b](/cfr/21/522.313b.md), [522.313c](/cfr/21/522.313c.md), and [526.313](/cfr/21/526.313.md) of this chapter.

## Notes

### Authority

Authority: 21 U.S.C. 342, 360b, 371.

### Source

Source: 84 FR 32993, July 11, 2019, unless otherwise noted.