---
kind: "section"
citation: "21 C.F.R. § 529.400"
title: "21"
number: "529.400"
heading: "Chlorhexidine tablets and suspension."
url: "https://uscodex.org/cfr/21/529.400"
---

# §529.400. Chlorhexidine tablets and suspension.

- (a) **Specification.** Each tablet and each 28-milliliter syringe of suspension contain 1 gram of chlorhexidine dihydrochloride.
- (b) **Sponsor.** See No. 054771 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
- (c) **Related tolerances.** See [§ 556.120](/cfr/21/556.120.md) of this chapter.
- (d) **Conditions of use—**
  - (1) **Amount.** Place 1 or 2 tablets deep in each uterine horn; or infuse a solution of 1 tablet disolved in an appropriate amount of clean boiled water; or infuse one syringe of suspension into the uterus.
  - (2) **Indications for use.** For prevention or treatment of metritis and vaginitis in cows and mares when caused by pathogens sensitive to chlorhexidine dihydrochloride.
  - (3) **Limitations.** Prior to administration, remove any unattached placental membranes, any excess uterine fluid or debris, and carefully clean external genitalia. Use a clean, sterile inseminating pipette for administrating solutions and suspensions. Treatment may be repeated in 48 to 72 hours.

## Notes

### Amendments

[43 FR 10705, Feb. 23, 1979, as amended at 79 FR 10973, Feb. 27, 2014; 81 FR 67152, Sept. 30, 2016; 84 FR 32993, July 11, 2019]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13881, Mar. 27, 1975, unless otherwise noted.

### Amendments

[43 FR 10705, Feb. 23, 1979, as amended at 79 FR 10973, Feb. 27, 2014; 81 FR 67152, Sept. 30, 2016; 84 FR 32993, July 11, 2019]