---
kind: "section"
citation: "21 C.F.R. § 524.230"
title: "21"
number: "524.230"
heading: "Buprenorphine."
url: "https://uscodex.org/cfr/21/524.230"
---

# §524.230. Buprenorphine.

- (a) **Specifications.** Each milliliter (mL) of solution contains 20 milligrams (mg) buprenorphine. The drug is supplied in tubes containing 0.4 mL (8 mg) or 1.0 mL (20 mg).
- (b) **Sponsor.** See No. 058198 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
- (c) **Conditions of use in cats—**
  - (1) **Amount.** Administer topically to the dorsal cervical area at the base of the skull a single dose of 1.2 to 3.1 mg/lb (2.7 to 6.7 mg/kg) approximately 1 to 2 hours before surgery.
  - (2) **Indications for use.** For the control of postoperative pain associated with surgical procedures in cats.
  - (3) **Limitations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian. Buprenorphine is a Schedule III controlled substance.

## Notes

### Amendments

[87 FR 58962, Sept. 29, 2022]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13873, Mar. 27, 1975, unless otherwise noted.

### Amendments

[87 FR 58962, Sept. 29, 2022]