---
kind: "section"
citation: "21 C.F.R. § 522.480"
title: "21"
number: "522.480"
heading: "Corticotropin."
url: "https://uscodex.org/cfr/21/522.480"
---

# §522.480. Corticotropin.

- (a) **Specifications.** Each milliliter of aqueous solution contains 40 or 80 U.S.P. (I.U.) units of repository corticotropin.
- (b) **Sponsor.** See No. 061133 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
  - (1) **No.** 061133 for use as in paragraphs [(c)(1)](#c-1) and [(2)](#c-2) of this section.
  - (2) **No.** 043264 for use as in paragraph [(c)(2)](#c-2) and (3) of this section.
- (c) **Conditions of use—**
  - (1) **Dogs—**
    - (i) **Amount.** Administer one unit per pound of body weight by intramuscular injection.
    - (ii) **Indications for use.** As a diagnostic aid to test for adrenal dysfunction.
    - (iii) **Limitations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian.
  - (2) **Dogs and cats—**
    - (i) **Amount.** Administer one unit per pound of body weight by intramuscular or subcutaneous injection, to be repeated as indicated.
    - (ii) **Indications for use.** For stimulation of the adrenal cortex where there is a general deficiency of corticotropin (ACTH).
    - (iii) **Limitations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian.

## Notes

### Amendments

[79 FR 16185, Mar. 25, 2014, as amended at 84 FR 8973, Mar. 13, 2019; 85 FR 45308, July 28, 2020; 90 FR 40970, Aug. 22, 2025]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13858, Mar. 27, 1975, unless otherwise noted.

### Amendments

[79 FR 16185, Mar. 25, 2014, as amended at 84 FR 8973, Mar. 13, 2019; 85 FR 45308, July 28, 2020; 90 FR 40970, Aug. 22, 2025]