---
kind: "section"
citation: "21 C.F.R. § 522.454"
title: "21"
number: "522.454"
heading: "Clodronate."
url: "https://uscodex.org/cfr/21/522.454"
---

# §522.454. Clodronate.

- (a) **Specifications.** Each milliliter of solution contains 60 milligrams (mg) clodronate disodium.
- (b) **Sponsor.** See No. 043264 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
- (c) **Conditions of use in horses—**
  - (1) **Amount.** Administer 1.8 mg per kilogram of body weight by intramuscular injection up to a maximum dose of 900 mg per horse.
  - (2) **Indications for use.** For the control of clinical signs associated with navicular syndrome.
  - (3) **Limitations.** Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

## Notes

### Amendments

[79 FR 37620, July 2, 2014]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13858, Mar. 27, 1975, unless otherwise noted.

### Amendments

[79 FR 37620, July 2, 2014]