---
kind: "section"
citation: "21 C.F.R. § 522.2444b"
title: "21"
number: "522.2444b"
heading: "Thiopental and pentobarbital powder for injection."
url: "https://uscodex.org/cfr/21/522.2444b"
---

# §522.2444b. Thiopental and pentobarbital powder for injection.

- (a) **Specifications.** Each gram of powder contains 750 milligrams (mg) of sodium thiopental and 250 mg of sodium pentobarbital powder for dilution with sterile water for injection.
- (b) **Sponsor.** See No. 061133 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
- (c) **Conditions of use—**
  - (1) **Amount.** For total anesthesia, it is given at approximately 10 to 12 mg per pound of body weight over a period of 3.5 to 5 minutes. When preanesthetic medication is used, wait at least an hour before administering thiopental and sodium pentobarbital for injection, and the dosage necessary for anesthesia is reduced. Usually 1/2 to 2/3 the normal amount is adequate.
  - (2) **Indications for use.** It is used as an anesthetic for intravenous administration to dogs and cats during short to moderately long surgical procedures.
  - (3) **Limitations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian.

## Notes

### Amendments

[79 FR 16197, Mar. 25, 2014, as amended at 84 FR 8974, Mar. 13, 2019]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13858, Mar. 27, 1975, unless otherwise noted.

### Amendments

[79 FR 16197, Mar. 25, 2014, as amended at 84 FR 8974, Mar. 13, 2019]