---
kind: "section"
citation: "21 C.F.R. § 522.1410"
title: "21"
number: "522.1410"
heading: "Methylprednisolone."
url: "https://uscodex.org/cfr/21/522.1410"
---

# §522.1410. Methylprednisolone.

- (a) **Specifications.** Each milliliter of suspension contains 20 or 40 milligrams (mg) of methylprednisolone acetate.
- (b) **Sponsors.** See Nos. 054771 and 069043 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
- (c) [Reserved]
- (d) **Conditions of use—**
  - (1) **Dogs—**
    - (i) **Amount.** Administer 2 to 40 mg (up to 120 mg in extremely large breeds or dogs with severe involvement) by intramuscular injection or up to 20 mg by intrasynovial injection.
    - (ii) **Indications for use.** For treatment of inflammation and related disorders; treatment of allergic and dermatologic disorders; and as supportive therapy to antibacterial treatment of severe infections.
    - (iii) **Limitations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian.
  - (2) **Cats—**
    - (i) **Amount.** Administer 10 to 20 mg by intramuscular injection.
    - (ii) **Indications for use.** For treatment of inflammation and related disorders; treatment of allergic and dermatologic disorders; and as supportive therapy to antibacterial treatment of severe infections.
    - (iii) **Limitations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian.
  - (3) **Horses—**
    - (i) **Amount.** Administer 200 mg by intramuscular injection or 40 to 240 mg by intrasynovial injection.
    - (ii) **Indications for use.** For treatment of inflammation and related disorders.
    - (iii) **Limitations.** Do not use in horses intended for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

## Notes

### Amendments

[43 FR 59058, Dec. 19, 1978, as amended at 51 FR 741, Jan. 8, 1986; 53 FR 40728, Oct. 18, 1988; 62 FR 35076, June 30, 1997; 76 FR 53051, Aug. 25, 2011; 78 FR 21060, Apr. 9, 2013; 79 FR 16191, Mar. 25, 2014; 83 FR 48946, Sept. 28, 2018]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13858, Mar. 27, 1975, unless otherwise noted.

### Amendments

[43 FR 59058, Dec. 19, 1978, as amended at 51 FR 741, Jan. 8, 1986; 53 FR 40728, Oct. 18, 1988; 62 FR 35076, June 30, 1997; 76 FR 53051, Aug. 25, 2011; 78 FR 21060, Apr. 9, 2013; 79 FR 16191, Mar. 25, 2014; 83 FR 48946, Sept. 28, 2018]