---
kind: "section"
citation: "21 C.F.R. § 522.1222"
title: "21"
number: "522.1222"
heading: "Ketamine."
url: "https://uscodex.org/cfr/21/522.1222"
---

# §522.1222. Ketamine.

- (a) **Specifications.** Each milliliter contains ketamine hydrochloride equivalent to 100 milligrams (mg) ketamine base activity.
- (b) **Sponsors.** See Nos. 00010, 017033, 054771, 058198, 059399, and 069043 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
- (c) **Special considerations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian.
- (d) **Conditions of use—**
  - (1) **Cats—**
    - (i) **Amount.** 5 to 15 mg/pound body weight intramuscularly, depending on the effect desired.
    - (ii) **Indications for use.** For restraint or as the sole anesthetic agent in diagnostic or minor, brief surgical procedures that do not require skeletal muscle relaxation.
  - (2) **Subhuman primates—**
    - (i) **Amount.** 3 to 15 mg/kilogram body weight intramuscularly, depending upon the species, general condition, and age of the subject.
    - (ii) **Indications for use.** For restraint.

## Notes

### Amendments

[67 FR 17283, Apr. 10, 2002, as amended at 73 FR 8192, Feb. 13, 2008. Redesignated at 79 FR 16191, Mar. 25, 2014, as amended at 80 FR 13229, Mar. 13, 2015; 83 FR 48946, Sept. 28, 2018; 86 FR 14820, Mar. 19, 2021; 88 FR 27699, May 3, 2023; 88 FR 55564, Aug. 16, 2023]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13858, Mar. 27, 1975, unless otherwise noted.

### Amendments

[67 FR 17283, Apr. 10, 2002, as amended at 73 FR 8192, Feb. 13, 2008. Redesignated at 79 FR 16191, Mar. 25, 2014, as amended at 80 FR 13229, Mar. 13, 2015; 83 FR 48946, Sept. 28, 2018; 86 FR 14820, Mar. 19, 2021; 88 FR 27699, May 3, 2023; 88 FR 55564, Aug. 16, 2023]