---
kind: "section"
citation: "21 C.F.R. § 520.2158"
title: "21"
number: "520.2158"
heading: "Streptomycin."
url: "https://uscodex.org/cfr/21/520.2158"
---

# §520.2158. Streptomycin.

- (a) **Specifications.** Each milliliter of solution contains 250 milligrams (25 percent) streptomycin sulfate.
- (b) **Sponsor.** See No. 016592 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
- (c) **Related tolerances.** See [§ 556.610](/cfr/21/556.610.md) of this chapter.
- (d) **Conditions of use.** Use in drinking water as follows:
  - (1) **Calves—**
    - (i) **Amount.** 10 to 15 milligrams per pound (mg/pound) of body weight (1.0 to 1.5 grams per gallon) for up to 5 days.
    - (ii) **Indications for use.** For the treatment of bacterial enteritis caused by Escherichia coli and Salmonella spp. susceptible to streptomycin.
    - (iii) **Limitations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian.
  - (2) **Swine—**
    - (i) **Amount.** 10 to 15 mg/pound of body weight (1.0 to 1.5 grams per gallon) for up to 4 days.
    - (ii) **Indications for use.** For the treatment of bacterial enteritis caused by Escherichia coli and Salmonella spp. susceptible to streptomycin.
    - (iii) **Limitations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian.
  - (3) **Chickens—**
    - (i) **Amount.** 10 to 15 mg/pound of body weight (0.6 to 0.9 grams per gallon) for up to 5 days.
    - (ii) **Indications for use.** For the treatment of nonspecific infectious enteritis caused by organisms susceptible to streptomycin.
    - (iii) **Limitations.** Withdraw 4 days before slaughter. Do not administer to chickens producing eggs for human consumption. Federal law restricts this drug to use by or on the order of a licensed veterinarian.

## Notes

### Amendments

[57 FR 37327, Aug. 18, 1992, as amended at 58 FR 47211, Sept. 8, 1993; 63 FR 51821, Sept. 29, 1998. Redesignated and amended at 79 FR 28828, May 20, 2014; 79 FR 74020, Dec. 15, 2014; 80 FR 18776, Apr. 8, 2015; 80 FR 61296, Oct. 13, 2015]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13838, Mar. 27, 1975, unless otherwise noted.

### Amendments

[57 FR 37327, Aug. 18, 1992, as amended at 58 FR 47211, Sept. 8, 1993; 63 FR 51821, Sept. 29, 1998. Redesignated and amended at 79 FR 28828, May 20, 2014; 79 FR 74020, Dec. 15, 2014; 80 FR 18776, Apr. 8, 2015; 80 FR 61296, Oct. 13, 2015]