---
kind: "section"
citation: "21 C.F.R. § 520.154a"
title: "21"
number: "520.154a"
heading: "Bacitracin methylenedisalicylate."
url: "https://uscodex.org/cfr/21/520.154a"
---

# §520.154a. Bacitracin methylenedisalicylate.

- (a) **Specifications.** Each pound of soluble powder contains the equivalent of 50 grams of bacitracin activity for use as in paragraph [(d)(1)](#d-1) or [(d)(2)](#d-2) of this section, or the equivalent of 200 grams of bacitracin activity for use as in [paragraph (d)](#d) of this section.
- (b) **Sponsor.** See No. 054771 in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter.
- (c) **Related tolerances.** See [§ 556.70](/cfr/21/556.70.md) of this chapter.
- (d) **Conditions of use—**
  - (1) **Broiler and replacement chickens—**
    - (i) **Amount.** 100 mg per gal in drinking water.
      - (A) **Indications for use.** Aid in the prevention of necrotic enteritis caused by Clostridium perfringens susceptible to bacitracin methylenedisalicylate.
      - (B) **Limitations.** Prepare a fresh solution daily. Use as the sole source of drinking water.
    - (ii) **Amount.** 200 to 400 mg per gal in drinking water. Administer continuously 5 to 7 days or as long as clinical signs persist, then reduce to prevention levels (100 mg/gal).
      - (A) **Indications for use.** Treatment of necrotic enteritis caused by C. perfringens susceptible to bacitracin methylenedisalicylate.
      - (B) **Limitations.** Prepare a fresh solution daily. Use as the sole source of drinking water.
  - (2) **Growing turkeys—**
    - (i) **Amount.** 400 milligrams (mg) per gallon (gal) in drinking water.
    - (ii) **Indications for use.** Aid in the control of transmissible enteritis complicated by organisms susceptible to bacitracin methylenedisalicylate.
    - (iii) **Limitations.** Prepare a fresh solution daily. Use as the sole source of drinking water.
  - (3) **Swine—**
    - (i) **Amount.** 1 gram per gallon in drinking water.
    - (ii) **Indications for use.** Treatment of swine dysentery associated with Brachyspira hyodysenteriae. Administer continuously for 7 days or until signs of dysentery disappear.
    - (iii) **Limitations.** Prepare a fresh solution daily. Use as the sole source of drinking water. Treatment not to exceed 14 days. Not to be given to swine that weigh more than 250 pounds.
  - (4) **Growing quail—**
    - (i) **Amount.** 400 mg per gal in drinking water.
    - (ii) **Indications for use.** For prevention of ulcerative enteritis due to Clostridium colinum susceptible to bacitracin methylenedisalicylate.
    - (iii) **Limitations.** Prepare fresh solution daily. Use as sole source of drinking water.

## Notes

### Amendments

[57 FR 37322, Aug. 18, 1992; 57 FR 42623, Sept. 15, 1992, as amended at 63 FR 38474, July 17, 1998; 64 FR 13068, Mar. 17, 1999; 76 FR 53050, Aug. 25, 2011; 79 FR 28818, May 20, 2014; 80 FR 34278, June 16, 2015; 88 FR 14897, Mar. 10, 2023]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13838, Mar. 27, 1975, unless otherwise noted.

### Amendments

[57 FR 37322, Aug. 18, 1992; 57 FR 42623, Sept. 15, 1992, as amended at 63 FR 38474, July 17, 1998; 64 FR 13068, Mar. 17, 1999; 76 FR 53050, Aug. 25, 2011; 79 FR 28818, May 20, 2014; 80 FR 34278, June 16, 2015; 88 FR 14897, Mar. 10, 2023]