---
kind: "section"
citation: "21 C.F.R. § 520.1242a"
title: "21"
number: "520.1242a"
heading: "Levamisole powder."
url: "https://uscodex.org/cfr/21/520.1242a"
---

# §520.1242a. Levamisole powder.

- (a) **Specifications.** Each package of powder contains 9.075, 11.7, 18.15, 46.8, 362.7, or 544.5 grams (g) levamisole hydrochloride.
- (b) **Sponsors.** See sponsors in [§ 510.600(c)](/cfr/21/510.600.md?p=c) for use as follows:
  - (1) **No.** 000061 for use of 46.8- and 544.5-g packages as in paragraph [(e)(1)(i)](#e-1-i), [(e)(1)(ii)(B)](#e-1-ii-B), and (e)(1)(iii) of this section; for 11.7-, 46.8-, and 544.5-g packages as in paragraph [(e)(2)(i)](#e-2-i), [(e)(2)(ii)(B)](#e-2-ii-B), and (e)(2)(iii) of this section; and for an 18.15-g package as in [paragraph (e)(3)](#e-3) of this section.
  - (2) **No.** 054771 for use of a 46.8-g package as in paragraph [(e)(1)(i)](#e-1-i), [(e)(1)(ii)(A)](#e-1-ii-A), and (e)(1)(iii) of this section; for 11.7- and 46.8-g packages as in paragraph [(e)(2)(i)](#e-2-i), [(e)(2)(ii)(A)](#e-2-ii-A), and (e)(2)(iii) of this section; and for 9.075- and 18.15-g packages as in [paragraph (e)(3)](#e-3) of this section.
  - (3) **No.** 016592 for use of 46.8- and 544.5-g packages as in paragraphs [(e)(1)(i)](#e-1-i), [(e)(1)(ii)(B)](#e-1-ii-B), and (e)(1)(iii) and (e)(2)(i), [(e)(2)(ii)(B)](#e-2-ii-B), and (e)(2)(iii) of this section.
  - (4) **No.** 061133 for use of 46.8-, 362.7-, and 544.5-g packages as in paragraphs [(e)(1)(i)](#e-1-i), [(e)(1)(ii)(B)](#e-1-ii-B), (e)(1)(iii), (e)(2)(i), [(e)(2)(ii)(B)](#e-2-ii-B), and (e)(2)(iii) of this section; and for use of an 18.15-g package as in [paragraph (e)(3)](#e-3) of this section.
- (c) **Related tolerances.** See [§ 556.350](/cfr/21/556.350.md) of this chapter.
- (d) **Special considerations.** See [§ 500.25](/cfr/21/500.25.md) of this chapter.
- (e) **Conditions of use.** It is used as an anthelmintic as follows:
  - (1) **Cattle—**
    - (i) **Amount.** 8 milligrams per kilogram (mg/kg) body weight as a drench.
    - (ii) **Indications for use.**
      - (A) **Effective against the following nematode infections—** Stomach worms (Haemonchus, Trichostrongylus, Ostertagia); intestinal worms (Trichostrongylus, Cooperia, Nematodirus, Bunostomum, Oesophagostomum); and lungworms (Dictyocaulus).
      - (B) **Effective against the following adult nematode infections—** Stomach worms (Haemonchus placei, Ostertagia ostertagi, Trichostrongylus axei); intestinal worms (T. longispicularis, Cooperia oncophora, C. punctata, Nematodirus spathiger, Bunostomum phlebotomum, Oesophagostomum radiatum); and lungworms (Dictyocaulus viviparus).
    - (iii) **Limitations.** Do not slaughter for food within 48 hours of treatment. Not for use in dairy animals of breeding age. Conditions of constant helminth exposure may require retreatment 2 to 4 weeks after the first treatment. Consult your veterinarian before using in severely debilitated animals.
  - (2) **Sheep—**
    - (i) **Amount.** 8 mg/kg body weight as a drench.
    - (ii) **Indications for use.**
      - (A) **Effective against the following nematode infections—** Stomach worms (Haemonchus, Trichostrongylus, Ostertagia); intestinal worms (Trichostrongylus, Cooperia, Nematodirus, Bunostomum, Oesophagostomum, Chabertia); and lungworms (Dictyocaulus).
      - (B) **Effective against the following adult nematode infections—** Stomach worms (Haemonchus contortus, Trichostrongylus axei, Teladorsagia circumcincta); intestinal worms (Trichostrongylus colubriformis, Cooperia curticei, Nematodirus spathiger, Bunostomum trigonocephalum, Oesophagostomum columbianum, Chabertia ovina), and lungworms (Dictyocaulus filaria).
    - (iii) **Limitations.** Do not slaughter for food within 72 hours of treatment. Conditions of constant helminth exposure may require retreatment 2 to 4 weeks after the first treatment. Consult veterinarian before using in severely debilitated animals.
  - (3) **Swine—**
    - (i) **Amount.** 8 mg/kg body weight in drinking water.
    - (ii) **Indications for use.** Effective against the following nematode infections: Large roundworms (Ascaris suum), nodular worms (Oesophagostomum spp.), intestinal thread worms (Strongyloides ransomi) and lungworms (Metastrongylus spp. ).
    - (iii) **Limitations.** Do not administer within 72 hours of slaughter for food. Pigs maintained under conditions of constant exposure to worms may require retreatment within 4 to 5 weeks after the first treatment. Consult your veterinarian before administering to sick swine.

## Notes

### Amendments

[69 FR 9753, Mar. 2, 2004, as amended at 69 FR 33839, June 17, 2004; 70 FR 2353, Jan. 13, 2005; 77 FR 28253, May 14, 2012; 78 FR 28822, May 20, 2014; 84 FR 8972, Mar. 13, 2019; 87 FR 58961, Sept. 29, 2022]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13838, Mar. 27, 1975, unless otherwise noted.

### Amendments

[69 FR 9753, Mar. 2, 2004, as amended at 69 FR 33839, June 17, 2004; 70 FR 2353, Jan. 13, 2005; 77 FR 28253, May 14, 2012; 78 FR 28822, May 20, 2014; 84 FR 8972, Mar. 13, 2019; 87 FR 58961, Sept. 29, 2022]