---
kind: "section"
citation: "21 C.F.R. § 520.1193"
title: "21"
number: "520.1193"
heading: "Ivermectin tablets and chewables."
url: "https://uscodex.org/cfr/21/520.1193"
---

# §520.1193. Ivermectin tablets and chewables.

- (a) **Specifications.**
  - (1) **Each tablet or chewable contains 68, 136, or 272 micrograms (mcg) ivermectin.**
  - (2) **Each chewable contains 55 or 165 mcg ivermectin.**
- (b) **Sponsors.** See sponsors in [§ 510.600(c)](/cfr/21/510.600.md?p=c) of this chapter for use as in [paragraph (d)](#d) of this section.
  - (1) **No.** 000010 for use of tablets or chewables described in [paragraph (a)(1)](#a-1) as in [paragraph (d)(1)](#d-1) and chewables described in [paragraph (a)(2)](#a-2) as in [paragraph (d)(2)](#d-2) of this section.
  - (2) **Nos.** 051311 and 069043 for use of tablets described in [paragraph (a)(1)](#a-1) as in [paragraph (d)(1)](#d-1) of this section.
- (c) **Special considerations.** Federal law restricts this drug to use by or on the order of a licensed veterinarian.
- (d) **Conditions of use—**
  - (1) **Dogs.** For use in dogs 6 weeks of age and older as follows:
    - (i) **Amount.** 6.0 mcg per kilogram (kg) of body weight (2.72 mcg per pound (lb)), minimum. Up to 25 lb, 68 mcg; 26 to 50 lb, 136 mcg; 51 to 100 lb, 272 mcg; over 100 lb, a combination of the appropriate tablets. Administer at monthly dosing intervals.
    - (ii) **Indications for use.** To prevent canine heartworm disease by eliminating the tissue stage of heartworm larvae (Dirofilaria immitis) for 1 month (30 days) after infection.
  - (2) **Cats.** For use in cats 6 weeks of age and older as follows:
    - (i) **Amount.** Up to 2.3 kilograms (up to 5 lb), 55 mcg; 2.3 to 6.8 kilograms (5 to 15 lb), 165 mcg; over 6.8 kilograms (15 lb), a combination of the appropriate chewables (recommended minimum dose of 24 mcg/kg of body weight (10.9 mcg/lb)). Administer once a month.
    - (ii) **Indications for use.** To prevent feline heartworm disease by eliminating the tissue stage of heartworm larvae Dirofilaria immitis for a month (30 days) after infection, and for removal and control of adult and immature (L4) hookworms Ancylostoma tubaeforme and A. braziliense.

## Notes

### Amendments

[67 FR 11230, Mar. 13, 2002, as amended at 67 FR 21996, May 2, 2002; 69 FR 43735, July 22, 2004; 81 FR 17607, Mar. 30, 2016; 84 FR 39183, Aug. 9, 2019]

### Authority

Authority: 21 U.S.C. 360b.

### Source

Source: 40 FR 13838, Mar. 27, 1975, unless otherwise noted.

### Amendments

[67 FR 11230, Mar. 13, 2002, as amended at 67 FR 21996, May 2, 2002; 69 FR 43735, July 22, 2004; 81 FR 17607, Mar. 30, 2016; 84 FR 39183, Aug. 9, 2019]