---
kind: "section"
citation: "21 C.F.R. § 500.92"
title: "21"
number: "500.92"
heading: "Implementation."
url: "https://uscodex.org/cfr/21/500.92"
---

# §500.92. Implementation.

- (a) This subpart E applies to all new animal drug applications, food additive petitions, color additive petitions, and requests for import tolerances concerning any compound intended for use in food-producing animals (including supplemental applications and amendments to petitions).
- (b) This subpart E also applies in the following manner to compounds already approved:
  - (1) For those compounds that FDA determines may induce cancer when ingested by man or animals, i.e., suspect carcinogens, §§ [500.80(b)](/cfr/21/500.80.md?p=b), [500.82](/cfr/21/500.82.md), and [500.90](/cfr/21/500.90.md) apply.
  - (2) For those compounds that FDA determines have been shown to induce cancer when ingested by man or animals, [§§ 500.82 through 500.90](/cfr/21/500.82..500.90.md) apply.

## Notes

### Amendments

[52 FR 49586, Dec. 31, 1987, as amended at 86 FR 52410, Sept. 21, 2021]

### Source

Source: 52 FR 49586, Dec. 31, 1987, unless otherwise noted.

### Authority

Authority: 21 U.S.C. 321, 331, 342, 343, 348, 351, 352, 353, 360b, 371, 379e.

### Source

Source: 40 FR 13802, Mar. 27, 1975, unless otherwise noted.

### Amendments

[52 FR 49586, Dec. 31, 1987, as amended at 86 FR 52410, Sept. 21, 2021]